Professor Chao-Hsiung Lin, one member of our research team, has long been focused on using metabolomics to explore the molecular mechanisms of aging and disease. The research results were published in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences. The article utilized a long-term cohort study on aging in Yuanshan (710 Taiwanese subjects) to establish a plasma metabolite biomarker model that reflects biological age. The findings suggest that sebacic acid and other ω-oxidation metabolites may be common aging biomarkers in humans and mice. It is hypothesized that sebacic acid plays an energy-supporting role in the production of acetyl-CoA during liver aging. Changes in its plasma levels reflect the aging process and can serve as biomarkers for future research on liver aging. Additionally, an article published in the International Journal of Molecular Sciences elucidates that Galgravin, a lignan found in Schisandra chinensis, can reduce the production of inflammatory and related immune factors by inhibiting the NF-κB pathway. This may help mitigate tissue and organ damage caused by infections. Since chronic low-grade inflammation is a key feature of the aging process, Galgravin, which can inhibit inflammatory cytokines without significant cytotoxicity, shows promise as a candidate natural compound for anti-aging effects.