Social Contributions

Here’s a brief summary of the societal contributions generated by our center through past and future projects:

Our center has been devoted to addressing the various challenges arising from population aging for many years. We have achieved significant milestones in academic research, becoming an internationally recognized research team. Our focus extends to numerous local issues, such as healthcare services and health promotion, through in-depth research. Our research outcomes have garnered attention from governmental departments, leading to their inclusion in national policies. We have been invited to collaborate with governments at all levels to promote policy implementation, thereby expanding the influence of our research on the general population.

Furthermore, our research outcomes have facilitated extensive collaboration with the business sector, fostering industry-academia cooperation. We have successfully transferred research and development outcomes into technological innovations and commercial designs, promoting their adoption both domestically and internationally. This has contributed to advancing the quality of life for elderly individuals, supporting the development of the silver economy, and fostering talent cultivation and international cooperation. Our efforts have had multifaceted impacts on national and international societies as they face demographic transitions towards aging populations. We strive to contribute to the transformation needed for an ultra-aging society.

Developing Evidence-based and Technologically Innovative Strategies for Healthy Longevity

Due to the unprecedented phenomenon of rapid population aging, there’s a pressing need for large-scale interdisciplinary innovation strategies. Both the United Nations and the World Health Organization advocate for community-based approaches in promoting healthy aging. In 2017, the World Health Organization launched the “Integrated Care for Older People” initiative, complemented by the “Decade of Healthy Aging” from 2021 to 2030. These initiatives focus on developing interdisciplinary scientific evidence and community-based interventions to drive societal redesign. Our center, through interdisciplinary research spanning biology, clinical medicine, public health, information science, and artificial intelligence, implements concrete initiatives in various communities domestically. These initiatives hold substantial practical value for national efforts to promote healthy aging and enhance public health. Additionally, our center plans to implement community-based interventions in Taipei, New Taipei, Yilan, Hsinchu, and Taichung, leveraging community resources to promote tangible practices. These efforts aim to improve the health of the population and compress unhealthy lifespans, ultimately achieving the overarching goal of healthy aging. By translating foundational scientific research into community interventions, we aim to develop evidence-based strategies for promoting high-quality community health.

Our center began conducting local generational studies in Taiwan a decade ago. Currently, we have three ongoing aging cohort studies. One such study, conducted in collaboration with Taipei Veterans General Hospital, focuses on the Yilan aging cohort. This study has been ongoing for ten years (fourth wave), gaining international recognition and yielding numerous epidemiological and healthy aging research outcomes. Additionally, considering the differences between urban and rural areas, we initiated the Taipei-New Taipei Aging Cohort Study, which has been ongoing for over five years (second wave). This study aims to compare aging characteristics and healthcare needs between urban and rural populations aged 50 and above. Recognizing the unique health characteristics of the elderly, our center commenced a longitudinal cohort study of individuals aged 85 and above in Taichung since 2021. These three cohort studies complement each other, providing a comprehensive overview of Taiwan’s aging population. The high-quality data collected, including genetics, serum, imaging, and clinical data, serve as a research platform for healthy aging. We also progressively engage in international cooperation and comparative research to explore specific health aging characteristics unique to the Taiwanese population and develop corresponding strategies.

With the support of the Taiwan Ministry of Health and Welfare and the National Health Research Institutes, our center has designed and executed the Taiwan Health Promotion Intervention Study of Community-Dwelling Elders (THISCE) and the Taiwan Integrated GERiatric Care Study (TIGER). These studies, characterized by high-level randomized controlled experiments, have garnered the highest level of evidence. Not only have their research outcomes received international recognition, but they have also become crucial evidence for promoting healthy aging domestically and internationally. The TIGER study was published in Lancet Healthy Longevity in 2022, establishing a multifaceted intervention model suitable for Taiwanese older adults and confirming its effectiveness. With a strong foundation in academic research and an extensive international cooperation network, these studies have exerted significant influence on both Taiwanese and international societies.

Based on these significant research outcomes, the “Prevention and Delay of Disability” policies of Taiwan’s Long-term Care 2.0 initiative have extensively adopted our center’s research designs for nationwide implementation. This implementation is being carried out in health centers across various counties and cities, receiving excellent responses from local health authorities and the Ministry of Health and Welfare. There are plans to further integrate these policies as the main national implementation models, with the expectation of effectively reducing unhealthy lifespans among the population. Additionally, our center, in collaboration with the Aging Medical Center team at Taipei Veterans General Hospital, has developed integrated outpatient clinics, integrated care in geriatric medical wards, acute post-acute care, and integrated models for day care centers. These research outcomes with local characteristics have become policy references for the National Health Insurance Administration and the Ministry of Health and Welfare, gradually becoming the core of the national health care system.

In summary, the social contributions generated by our research outcomes are consistently focused on utilizing rigorous research designs and academic findings to address the issues arising from population aging in Taiwan. These high-quality academic research outcomes serve as the foundation for policy-making, facilitating evidence-based policy-making efforts. This approach allows Taiwan to plan strategies in line with scientific evidence amid rapid demographic shifts towards aging populations.

Promoting the Silver Economy Ecosystem through Innovative Technological Research and Development Outcomes

Due to the rapid advancements in biomedical sciences and information and communication technology, coupled with the unprecedented phenomenon of rapid population aging, it’s imperative to generate new economic momentum to sustain societal development. Since its establishment, our center has actively translated research outcomes into practical applications. We have collaborated with media and the business sector to advocate for the development of the silver economy ecosystem, aiming to enhance the quality of life and promote healthy aging among middle-aged and elderly populations. We have transformed research outcomes into various products and services, increasing public access to high-quality research outcomes and driving national economic development while enhancing Taiwan’s international competitiveness in the silver economy sector.

Our center has actively engaged in industry-academia collaboration. We collaborated with YouHua Biotech to develop the nutritional supplement “Jilijia” for muscular dystrophy. Through innovative nutritional supplement formulations and clinical trial outcomes, we effectively raised awareness of muscular dystrophy among the public and increased product sales. Furthermore, our research team collaborated with Guiguan Industrial Co., Ltd. to establish the “Guiguan Nutrition Research Lab” and develop frozen soup products tailored to the dietary habits of Taiwanese people. These products ensure sufficient daily intake of protein and dietary fiber for the elderly, gradually becoming mainstream products in the market. Additionally, leveraging the regulation of the Cisd2 longevity gene, we developed beauty products and transferred the technology to YouHua Biotech for product development and sales.

Through the analysis and application of artificial intelligence, our center collaborated with Acer Group to develop equipment for “facial recognition prediction of dementia behavioral symptoms,” which not only won national innovation awards but also successfully entered the market through technology transfer and was sold to domestic long-term care and day care centers. Furthermore, our center’s team collaborated with various companies, including Fubon Life Insurance, Fubon Insurance, Cathay Life Insurance, American Reinsurance Company, and Paris Life Insurance, to assist in clarifying the risks of disability and dementia during the aging process. By establishing health risk prediction models using wearable devices, we provided life insurance companies with the means to develop health promotion-related riders, combining personal financial mechanisms with artificial intelligence applications to enhance national health promotion motivation and behavior, improve rider product design, and enhance public safety through reasonable insurance mechanisms and premiums.

Additionally, our research team integrated innovative technologies such as gravity sensors, photonic technology applications, and artificial intelligence brain age prediction platforms to apply for patents and develop products. The Rabboni gravity sensor and APP development platform have already been launched. Various tests have been completed for bone and joint and neurodegenerative diseases, and applications such as gait analysis, Parkinson’s disease diagnosis, seizure prediction systems, degenerative spinal diseases, and posture assessment are under development and undergoing TFDA certification, aiming to enhance early diagnosis and treatment of degenerative diseases. The development of innovative digital diagnostic strategies for degenerative diseases can effectively improve the efficacy of existing clinical treatments and promote Taiwan’s leadership in upgrading global treatment for related degenerative diseases, leading to innovative changes and practical applications.

Enhancing the promotion of healthy longevity through interdisciplinary education

Our center has been continuously involved in professional and public education and outreach, aiming to enhance both professional and public awareness of healthy aging through interdisciplinary teamwork. By publishing a series of consensus papers by the Asian Working Group on Muscular Dystrophy, we have provided medical professionals in Asia with the basis for conducting research and interventions on muscular dystrophy, thereby increasing the attention to healthy aging across Asian countries. Additionally, our center hosts several seminars each year targeting professionals and the general public to promote the importance of healthy aging and strategies for achieving it. Furthermore, our team members regularly contribute to mass media by publishing articles and books, aiming to enhance public awareness of healthy aging from different perspectives.

Our research team actively participates in various exhibitions nationwide, including the Taiwan Medical Technology Expo, Assistive Device Expo, and MEDICA in Germany, among others. Through these exhibitions and accompanying lectures, we directly engage with frontline citizens and medical institutions, showcasing successful examples of community and medical institution efforts in promoting healthy aging. We also promote lifestyle changes through activities such as exercise, nutrition, and chronic disease management, thereby raising awareness and promoting action towards national health and longevity. Moreover, we collaborate with various media platforms such as United Daily News and Business Next Magazine to organize thematic forums, engaging in civic education and promoting topics related to healthy aging, retirement planning, and other relevant issues to foster a healthy aging society.

Currently, National Yang-Ming Chiao Tung University plans to launch the “Rejuvenation and Vitality – Active Aging Innovation Community” at its Bo-Ai Campus in Hsinchu, where our center will play a key role. This community will integrate four major dimensions: engineering biology, engineering medicine, social culture, and humanities medicine, with the core value goal of promoting preventive medicine and health promotion. It aims to construct an integrated service model for health care, medical treatment, smart management, rehabilitation, and empowerment. Furthermore, in addition to utilizing data and technology to create innovative healthcare, this community at the Bo-Ai Campus will focus on historical regeneration. It will utilize existing campus buildings while preserving historical and cultural heritage to create a platform for health and wellness that integrates technology innovation with local history and culture, aiming to align with international standards while building a unique platform tailored for the National Yang-Ming Chiao Tung University community.

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